Inhibition of sPLA(2)-IIA Prevents LPS-Induced Neuroinflammation by Suppressing ERK1/2-cPLA(2)α Pathway in Mice Cerebral Cortex

Neuroinflammation is involved in various central nervous system (CNS) disorders, including brain infections, ischemia, trauma, stroke, and degenerative CNS diseases. In the CNS inflammation, secretory phospholipase A(2)-IIA (sPLA(2)-IIA) acts as a mediator, resulting in the generation of the precurs...

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Detalles Bibliográficos
Autores principales: Xiang, Yanxiao, Chen, Lin, Liu, Huiqing, Liu, Xiaoqian, Wei, Xinbing, Sun, Baozhu, Wang, Tian, Zhang, Xiumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793966/
https://www.ncbi.nlm.nih.gov/pubmed/24130900
http://dx.doi.org/10.1371/journal.pone.0077909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793966/
https://www.ncbi.nlm.nih.gov/pubmed/24130900
http://dx.doi.org/10.1371/journal.pone.0077909

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