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CATP-6, a C. elegans Ortholog of ATP13A2 PARK9, Positively Regulates GEM-1, an SLC16A Transporter

In previous work, we found that gain-of-function mutations that hyperactivate GEM-1 (an SLC16A transporter protein) can bypass the requirement for GON-2 (a TRPM channel protein) during the initiation of gonadogenesis in C. elegans. Consequently, we proposed that GEM-1 might function as part of a Mg(...

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Detalles Bibliográficos
Autores principales: Lambie, Eric J., Tieu, Pamela J., Lebedeva, Nadja, Church, Diane L., Conradt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793975/
https://www.ncbi.nlm.nih.gov/pubmed/24130856
http://dx.doi.org/10.1371/journal.pone.0077202