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The Effect of p38MAPK on Cyclic Stretch in Human Facial Hypertrophic Scar Fibroblast Differentiation

Hypertrophic scars (HTS), the excessive deposition of scar tissue by fibroblasts, is one of the most common skin disorders. Fibroblasts derived from surgical scar tissue produce high levels of α-smooth muscle actin (α-SMA) and transforming growth factor-β1 (TGF-β1). However, the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Du, Qi-cui, Zhang, Dai-zun, Chen, Xiu-juan, Lan-Sun, Gui, Wu, Min, Xiao, Wen-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794006/
https://www.ncbi.nlm.nih.gov/pubmed/24130728
http://dx.doi.org/10.1371/journal.pone.0075635