ESAT-6 and HspX Improve the Effectiveness of BCG to Induce Human Dendritic Cells-Dependent Th1 and NK Cells Activation

The limited efficacy of the BCG vaccine against tuberculosis is partly due to the missing expression of immunogenic proteins. We analyzed whether the addition to BCG of ESAT-6 and HspX, two Mycobacterium tuberculosis (Mtb) antigens, could enhance its capacity to activate human dendritic cells (DCs)....

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Detalles Bibliográficos
Autores principales: Marongiu, Laura, Donini, Marta, Toffali, Lara, Zenaro, Elena, Dusi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794045/
https://www.ncbi.nlm.nih.gov/pubmed/24130733
http://dx.doi.org/10.1371/journal.pone.0075684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794045/
https://www.ncbi.nlm.nih.gov/pubmed/24130733
http://dx.doi.org/10.1371/journal.pone.0075684

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