Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly

The human extracellular matrix glycoprotein fibrillin-1 is the primary component of the 10- to 12-nm-diameter microfibrils, which perform key structural and regulatory roles in connective tissues. Relatively little is known about the molecular mechanisms of fibrillin assembly into microfibrils. Stud...

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Detalles Bibliográficos
Autores principales: Yadin, David A., Robertson, Ian B., McNaught-Davis, Joanne, Evans, Paul, Stoddart, David, Handford, Penny A., Jensen, Sacha A., Redfield, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794157/
https://www.ncbi.nlm.nih.gov/pubmed/24035709
http://dx.doi.org/10.1016/j.str.2013.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794157/
https://www.ncbi.nlm.nih.gov/pubmed/24035709
http://dx.doi.org/10.1016/j.str.2013.08.004

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