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MARCH5 inactivation supports mitochondrial function during neurodegenerative stress
Neuronal cell death is accompanied by mitochondrial dysfunction with mitochondrial maintenance critical to neuronal survival. The mitochondrial ubiquitin ligase MARCH5 has dual roles in the upkeep of mitochondrial function. MARCH5 is involved in targeted degradation of proteins harmful to mitochondr...
Autores principales: | Fang, Lei, Li, Jia, Flammer, Josef, Neutzner, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794199/ https://www.ncbi.nlm.nih.gov/pubmed/24133412 http://dx.doi.org/10.3389/fncel.2013.00176 |
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