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Methods and approaches in the topology-based analysis of biological pathways

The goal of pathway analysis is to identify the pathways significantly impacted in a given phenotype. Many current methods are based on algorithms that consider pathways as simple gene lists, dramatically under-utilizing the knowledge that such pathways are meant to capture. During the past few year...

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Detalles Bibliográficos
Autores principales: Mitrea, Cristina, Taghavi, Zeinab, Bokanizad, Behzad, Hanoudi, Samer, Tagett, Rebecca, Donato, Michele, Voichiţa, Călin, Drăghici, Sorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794382/
https://www.ncbi.nlm.nih.gov/pubmed/24133454
http://dx.doi.org/10.3389/fphys.2013.00278