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Interdomain Interactions Support Interdomain Communication in Human Pin1

[Image: see text] Pin1 is an essential mitotic regulator consisting of a peptidyl–prolyl isomerase (PPIase) domain flexibly tethered to a smaller Trp–Trp (WW) binding domain. Communication between these domains is important for Pin1 in vivo activity; however, the atomic basis for this communication...

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Detalles Bibliográficos
Autores principales: Wilson, Kimberly A., Bouchard, Jill J., Peng, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794440/
https://www.ncbi.nlm.nih.gov/pubmed/24020391
http://dx.doi.org/10.1021/bi401057x