Investigation into the Efficacy of Val-SN-38, a Valine-Ester Prodrug of the Anti-Cancer Agent SN-38

We recently reported that Val-SN-38, a novel valine ester prodrug of SN-38, had greatly improved the intracellular accumulation of SN-38 in MCF-7 cell line, probably through enhanced uptake via amino acid transporters. In the present study, the efficacy of Val-SN-38 was further investigated both in...

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Detalles Bibliográficos
Autores principales: Kwak, Eun-Young, Choi, Min-Koo, Yang, Su-Geun, Shim, Chang-Koo, Shim, Won-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794531/
https://www.ncbi.nlm.nih.gov/pubmed/24130931
http://dx.doi.org/10.4062/biomolther.2012.20.3.326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794531/
https://www.ncbi.nlm.nih.gov/pubmed/24130931
http://dx.doi.org/10.4062/biomolther.2012.20.3.326

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