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Differentially Methylated Loci Distinguish Ovarian Carcinoma Histological Types: Evaluation of a DNA Methylation Assay in FFPE Tissue

Epigenomic markers can identify tumor subtypes, but few platforms can accommodate formalin-fixed paraffin-embedded (FFPE) tumor tissue. We tested different amounts of bisulfite-converted (bs) DNA from six FFPE ovarian carcinomas (OC) of serous, endometrioid, and clear cell histologies and two HapMap...

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Detalles Bibliográficos
Autores principales: Kelemen, Linda E., Köbel, Martin, Chan, Angela, Taghaddos, Soreh, Dinu, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794544/
https://www.ncbi.nlm.nih.gov/pubmed/24175302
http://dx.doi.org/10.1155/2013/815894