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HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition

Epithelial-to-mesenchymal transition (EMT) is an embryonic program used by cancer cells to acquire invasive capabilities becoming metastatic. ΔRon, a constitutively active isoform of the Ron tyrosine kinase receptor, arises from skipping of Ron exon 11 and provided the first example of an alternativ...

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Detalles Bibliográficos
Autores principales: Bonomi, Serena, di Matteo, Anna, Buratti, Emanuele, Cabianca, Daphne S., Baralle, Francisco E., Ghigna, Claudia, Biamonti, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794575/
https://www.ncbi.nlm.nih.gov/pubmed/23863836
http://dx.doi.org/10.1093/nar/gkt579