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Minimal genome encoding proteins with constrained amino acid repertoire

Minimal bacterial gene set comprises the genetic elements needed for survival of engineered bacterium on a rich medium. This set is estimated to include 300–350 protein-coding genes. One way of simplifying an organism with such a minimal genome even further is to constrain the amino acid content of...

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Detalles Bibliográficos
Autores principales: Tsoy, Olga, Yurieva, Marina, Kucharavy, Andrey, O'Reilly, Mary, Mushegian, Arcady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794579/
https://www.ncbi.nlm.nih.gov/pubmed/23873957
http://dx.doi.org/10.1093/nar/gkt610