Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence

8-Oxoguanine (8-oxoG) is a major product of oxidative DNA damage, which induces replication errors and interferes with transcription. By varying the position of single 8-oxoG in a functional gene and manipulating the nucleotide sequence surrounding the lesion, we found that the degree of transcripti...

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Detalles Bibliográficos
Autores principales: Allgayer, Julia, Kitsera, Nataliya, von der Lippen, Carina, Epe, Bernd, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794583/
https://www.ncbi.nlm.nih.gov/pubmed/23863843
http://dx.doi.org/10.1093/nar/gkt620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794583/
https://www.ncbi.nlm.nih.gov/pubmed/23863843
http://dx.doi.org/10.1093/nar/gkt620

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