MREdictor: a two-step dynamic interaction model that accounts for mRNA accessibility and Pumilio binding accurately predicts microRNA targets

The prediction of pairing between microRNAs (miRNAs) and the miRNA recognition elements (MREs) on mRNAs is expected to be an important tool for understanding gene regulation. Here, we show that mRNAs that contain Pumilio recognition elements (PRE) in the proximity of predicted miRNA-binding sites ar...

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Detalles Bibliográficos
Autores principales: Incarnato, Danny, Neri, Francesco, Diamanti, Daniela, Oliviero, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794589/
https://www.ncbi.nlm.nih.gov/pubmed/23863844
http://dx.doi.org/10.1093/nar/gkt629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794589/
https://www.ncbi.nlm.nih.gov/pubmed/23863844
http://dx.doi.org/10.1093/nar/gkt629

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