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Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs

The exact role of intragenic DNA methylation in regulating tissue-specific gene regulation is unclear. Recently, the DNA-binding protein CTCF has been shown to participate in the regulation of alternative splicing in a DNA methylation-dependent manner. To globally evaluate the relationship between D...

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Detalles Bibliográficos
Autores principales: Wan, Jun, Oliver, Verity F., Zhu, Heng, Zack, Donald J., Qian, Jiang, Merbs, Shannath L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794605/
https://www.ncbi.nlm.nih.gov/pubmed/23887936
http://dx.doi.org/10.1093/nar/gkt652