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Automated and assisted RNA resonance assignment using NMR chemical shift statistics

The three-dimensional structure determination of RNAs by NMR spectroscopy relies on chemical shift assignment, which still constitutes a bottleneck. In order to develop more efficient assignment strategies, we analysed relationships between sequence and (1)H and (13)C chemical shifts. Statistics of...

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Detalles Bibliográficos
Autores principales: Aeschbacher, Thomas, Schmidt, Elena, Blatter, Markus, Maris, Christophe, Duss, Olivier, Allain, Frédéric H.-T., Güntert, Peter, Schubert, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794610/
https://www.ncbi.nlm.nih.gov/pubmed/23921634
http://dx.doi.org/10.1093/nar/gkt665