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In-gel probing of individual RNA conformers within a mixed population reveals a dimerization structural switch in the HIV-1 leader
Definitive secondary structural mapping of RNAs in vitro can be complicated by the presence of more than one structural conformer or multimerization of some of the molecules. Until now, probing a single structure of conformationally flexible RNA molecules has typically relied on introducing stabiliz...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794615/ https://www.ncbi.nlm.nih.gov/pubmed/23935074 http://dx.doi.org/10.1093/nar/gkt690 |