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Mitochondrial Dysfunction Induces Formation of Lipid Droplets as a Generalized Response to Stress

Lipid droplet (LD) formation is a hallmark of cellular stress. Cells attempt to combat noxious stimuli by switching their metabolism from oxidative phosphorylation to glycolysis, sparing resources in LDs for generating cellular reducing power and for anabolic biosynthesis. Membrane phospholipids are...

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Detalles Bibliográficos
Autores principales: Lee, Seon-Jin, Zhang, Jinglan, Choi, Augustine M. K., Kim, Hong Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794647/
https://www.ncbi.nlm.nih.gov/pubmed/24175011
http://dx.doi.org/10.1155/2013/327167