Low Amount of Salinomycin Greatly Increases Akt Activation, but Reduces Activated p70S6K Levels

The present study identified a novel salinomycin (Sal)-sensitization mechanism in cancer cells. We analyzed the signal proteins Akt, Jnk, p38, Jak, and Erk1/2 in cancer cell lines that had arrested growth following low amounts of Sal treatment. We also tested the signal molecules PI3K, PDK1, GSK3β,...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Hwa, Choi, Ae-Ran, Kim, Yong Kee, Kim, Hyung Sik, Yoon, Sungpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794729/
https://www.ncbi.nlm.nih.gov/pubmed/23975168
http://dx.doi.org/10.3390/ijms140917304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794729/
https://www.ncbi.nlm.nih.gov/pubmed/23975168
http://dx.doi.org/10.3390/ijms140917304

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