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Low Amount of Salinomycin Greatly Increases Akt Activation, but Reduces Activated p70S6K Levels
The present study identified a novel salinomycin (Sal)-sensitization mechanism in cancer cells. We analyzed the signal proteins Akt, Jnk, p38, Jak, and Erk1/2 in cancer cell lines that had arrested growth following low amounts of Sal treatment. We also tested the signal molecules PI3K, PDK1, GSK3β,...
Autores principales: | Kim, Ju-Hwa, Choi, Ae-Ran, Kim, Yong Kee, Kim, Hyung Sik, Yoon, Sungpil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794729/ https://www.ncbi.nlm.nih.gov/pubmed/23975168 http://dx.doi.org/10.3390/ijms140917304 |
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