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X-Ray Induced DNA Damage and Repair in Germ Cells of PARP1(−/−) Male Mice

Poly(ADP-ribose)polymerase-1 (PARP1) is a nuclear protein implicated in DNA repair, recombination, replication, and chromatin remodeling. The aim of this study was to evaluate possible differences between PARP1(−)(/)(−) and wild-type mice regarding induction and repair of DNA lesions in irradiated m...

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Detalles Bibliográficos
Autores principales: Villani, Paola, Fresegna, Anna Maria, Ranaldi, Roberto, Eleuteri, Patrizia, Paris, Lorena, Pacchierotti, Francesca, Cordelli, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794770/
https://www.ncbi.nlm.nih.gov/pubmed/24009020
http://dx.doi.org/10.3390/ijms140918078