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A Polymorphism at the 3′-UTR Region of the Aromatase Gene Is Associated with the Efficacy of the Aromatase Inhibitor, Anastrozole, in Metastatic Breast Carcinoma

Estrogen-related genes and the fat mass and obesity-associated (FTO) gene play a critical role in estrogen metabolism, and those polymorphisms are associated with a poor prognosis in breast cancer. However, little is known about the association between these polymorphisms and the efficacy of anastro...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Bai, Yu-Xian, Zhou, Jian-Hua, Sun, Xiu-Wei, Sui, Hong, Zhang, Wen-Jie, Yuan, Heng-Heng, Xie, Rui, Wei, Xiao-Li, Zhang, Ting-Ting, Huang, Peng, Li, Yan-Jing, Wang, Jing-Xuan, Zhao, Shu, Zhang, Qing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794816/
https://www.ncbi.nlm.nih.gov/pubmed/24065098
http://dx.doi.org/10.3390/ijms140918973