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A Polymorphism at the 3′-UTR Region of the Aromatase Gene Is Associated with the Efficacy of the Aromatase Inhibitor, Anastrozole, in Metastatic Breast Carcinoma
Estrogen-related genes and the fat mass and obesity-associated (FTO) gene play a critical role in estrogen metabolism, and those polymorphisms are associated with a poor prognosis in breast cancer. However, little is known about the association between these polymorphisms and the efficacy of anastro...
Autores principales: | Liu, Lei, Bai, Yu-Xian, Zhou, Jian-Hua, Sun, Xiu-Wei, Sui, Hong, Zhang, Wen-Jie, Yuan, Heng-Heng, Xie, Rui, Wei, Xiao-Li, Zhang, Ting-Ting, Huang, Peng, Li, Yan-Jing, Wang, Jing-Xuan, Zhao, Shu, Zhang, Qing-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794816/ https://www.ncbi.nlm.nih.gov/pubmed/24065098 http://dx.doi.org/10.3390/ijms140918973 |
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