Small Molecules Present in the Cerebrospinal Fluid Metabolome Influence Superoxide Dismutase 1 Aggregation

Superoxide dismutase 1 (SOD1) aggregation is one of the pathological markers of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder. The underlying molecular grounds of SOD1 pathologic aggregation remains obscure as mutations alone are not exclusively the cause for the formation...

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Detalles Bibliográficos
Autores principales: Cristóvão, Joana S., Leal, Sónia S., Cardoso, Isabel, Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794824/
https://www.ncbi.nlm.nih.gov/pubmed/24048249
http://dx.doi.org/10.3390/ijms140919128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794824/
https://www.ncbi.nlm.nih.gov/pubmed/24048249
http://dx.doi.org/10.3390/ijms140919128

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