Involvement of Calcium-Mediated Reactive Oxygen Species in Inductive GRP78 Expression by Geldanamycin in 9L Rat Brain Tumor Cells

Treatment with geldanamycin (GA) leads to an increase in [Ca(2+)](c) and the production of reactive oxygen species (ROS) in rat brain tumor 9L RBT cells. GA-exerted calcium signaling was blocked by BAPTA/AM and EGTA. The effect of GA on [Ca(2+)](c) was significantly reduced in the presence of thapsi...

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Detalles Bibliográficos
Autores principales: Sun, Fang-Chun, Shyu, Hsin-Yi, Lee, Meng-Shiou, Lee, Meng-Shiunn, Lai, Yiu-Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794827/
https://www.ncbi.nlm.nih.gov/pubmed/24051401
http://dx.doi.org/10.3390/ijms140919169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794827/
https://www.ncbi.nlm.nih.gov/pubmed/24051401
http://dx.doi.org/10.3390/ijms140919169

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