Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of Alox5 in Acute Myeloid Leukemia

Fusion protein RUNX1-ETO (AML1-ETO, RUNX1-RUNX1T1) is expressed as the result of the 8q22;21q22 translocation [t(8;21)], which is one of the most common chromosomal abnormalities found in acute myeloid leukemia. RUNX1-ETO is thought to promote leukemia development through the aberrant regulation of...

Descripción completa

Detalles Bibliográficos
Autores principales: DeKelver, Russell C., Lewin, Benjamin, Lam, Kentson, Komeno, Yukiko, Yan, Ming, Rundle, Chandler, Lo, Miao-Chia, Zhang, Dong-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794898/
https://www.ncbi.nlm.nih.gov/pubmed/24130502
http://dx.doi.org/10.1371/journal.pgen.1003765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794898/
https://www.ncbi.nlm.nih.gov/pubmed/24130502
http://dx.doi.org/10.1371/journal.pgen.1003765

Ejemplares similares