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Inferring Evolutionary Histories of Pathway Regulation from Transcriptional Profiling Data

One of the outstanding challenges in comparative genomics is to interpret the evolutionary importance of regulatory variation between species. Rigorous molecular evolution-based methods to infer evidence for natural selection from expression data are at a premium in the field, and to date, phylogene...

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Detalles Bibliográficos
Autores principales: Schraiber, Joshua G., Mostovoy, Yulia, Hsu, Tiffany Y., Brem, Rachel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794907/
https://www.ncbi.nlm.nih.gov/pubmed/24130471
http://dx.doi.org/10.1371/journal.pcbi.1003255