Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2

The budding yeast Srs2 is the archetype of helicases that regulate several aspects of homologous recombination (HR) to maintain genomic stability. Srs2 inhibits HR at replication forks and prevents high frequencies of crossing-over. Additionally, sensitivity to DNA damage and synthetic lethality wit...

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Detalles Bibliográficos
Autores principales: Esta, Aline, Ma, Emilie, Dupaigne, Pauline, Maloisel, Laurent, Guerois, Raphaël, Le Cam, Eric, Veaute, Xavier, Coïc, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794917/
https://www.ncbi.nlm.nih.gov/pubmed/24130504
http://dx.doi.org/10.1371/journal.pgen.1003833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794917/
https://www.ncbi.nlm.nih.gov/pubmed/24130504
http://dx.doi.org/10.1371/journal.pgen.1003833

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