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Inhibition of the Mitotic Exit Network in Response to Damaged Telomeres

When chromosomal DNA is damaged, progression through the cell cycle is halted to provide the cells with time to repair the genetic material before it is distributed between the mother and daughter cells. In Saccharomyces cerevisiae, this cell cycle arrest occurs at the G2/M transition. However, it i...

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Detalles Bibliográficos
Autores principales: Valerio-Santiago, Mauricio, de los Santos-Velázquez, Ana Isabel, Monje-Casas, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794921/
https://www.ncbi.nlm.nih.gov/pubmed/24130507
http://dx.doi.org/10.1371/journal.pgen.1003859