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Targeting Fungal Genes by Diced siRNAs: A Rapid Tool to Decipher Gene Function in Aspergillus nidulans

BACKGROUND: Gene silencing triggered by chemically synthesized small interfering RNAs (siRNAs) has become a powerful tool for deciphering gene function in many eukaryotes. However, prediction and validation of a single siRNA duplex specific to a target gene is often ineffective. RNA interference (RN...

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Detalles Bibliográficos
Autores principales: Kalleda, Natarajaswamy, Naorem, Aruna, Manchikatla, Rajam V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794931/
https://www.ncbi.nlm.nih.gov/pubmed/24130711
http://dx.doi.org/10.1371/journal.pone.0075443