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Molecular Dynamics Simulations of DNA-Free and DNA-Bound TAL Effectors

TAL (transcriptional activator-like) effectors (TALEs) are DNA-binding proteins, containing a modular central domain that recognizes specific DNA sequences. Recently, the crystallographic studies of TALEs revealed the structure of DNA-recognition domain. In this article, molecular dynamics (MD) simu...

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Detalles Bibliográficos
Autores principales: Wan, Hua, Hu, Jian-ping, Li, Kang-shun, Tian, Xu-hong, Chang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794935/
https://www.ncbi.nlm.nih.gov/pubmed/24130757
http://dx.doi.org/10.1371/journal.pone.0076045