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GCN2 in the Brain Programs PPARγ2 and Triglyceride Storage in the Liver during Perinatal Development in Response to Maternal Dietary Fat

The liver plays a central role in regulating lipid metabolism and facilitates efficient lipid utilization and storage. We discovered that a modest increase in maternal dietary fat in mice programs triglyceride storage in the liver of their developing offspring. The activation of this programming is...

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Detalles Bibliográficos
Autores principales: Xu, Xu, Hu, Jingjie, McGrath, Barbara C., Cavener, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794936/
https://www.ncbi.nlm.nih.gov/pubmed/24130751
http://dx.doi.org/10.1371/journal.pone.0075917