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Hypoxia Integration in the Serological Proteome Analysis Unmasks Tumor Antigens and Fosters the Identification of Anti-Phospho-eEF2 Antibodies as Potential Cancer Biomarkers

The expression by tumor cells of proteins with aberrant structure, expression or distribution accounts for the development of a humoral immune response. Autoantibodies (aAb) directed against tumor-associated antigens (TAA) may thus be particularly relevant for early detection of cancer. Serological...

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Detalles Bibliográficos
Autores principales: Grandjean, Marie, Sermeus, Alexandra, Branders, Samuel, Defresne, Florence, Dieu, Marc, Dupont, Pierre, Raes, Martine, De Ridder, Mark, Feron, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794947/
https://www.ncbi.nlm.nih.gov/pubmed/24130777
http://dx.doi.org/10.1371/journal.pone.0076508