Munc13-Like skMLCK Variants Cannot Mimic the Unique Calmodulin Binding Mode of Munc13 as Evidenced by Chemical Cross-Linking and Mass Spectrometry

Among the neuronal binding partners of calmodulin (CaM) are Munc13 proteins as essential presynaptic regulators that play a key role in synaptic vesicle priming and are crucial for presynaptic short-term plasticity. Recent NMR structural investigations of a CaM/Munc13-1 peptide complex have revealed...

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Detalles Bibliográficos
Autores principales: Herbst, Sabine, Maucher, Daniel, Schneider, Marian, Ihling, Christian H., Jahn, Olaf, Sinz, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794949/
https://www.ncbi.nlm.nih.gov/pubmed/24130683
http://dx.doi.org/10.1371/journal.pone.0075119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794949/
https://www.ncbi.nlm.nih.gov/pubmed/24130683
http://dx.doi.org/10.1371/journal.pone.0075119

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