Inheritable and Precise Large Genomic Deletions of Non-Coding RNA Genes in Zebrafish Using TALENs

Transcription activator-like effector nucleases (TALENs) have so far been applied to disrupt protein-coding genes which constitute only 2–3% of the genome in animals. The majority (70–90%) of the animal genome is actually transcribed as non-coding RNAs (ncRNAs), yet the lack of efficient tools to kn...

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Detalles Bibliográficos
Autores principales: Liu, Yun, Luo, Daji, Zhao, Hui, Zhu, Zuoyan, Hu, Wei, Cheng, Christopher H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794983/
https://www.ncbi.nlm.nih.gov/pubmed/24130773
http://dx.doi.org/10.1371/journal.pone.0076387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794983/
https://www.ncbi.nlm.nih.gov/pubmed/24130773
http://dx.doi.org/10.1371/journal.pone.0076387

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