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T Lymphocytes from Chronic HCV-Infected Patients Are Primed for Activation-Induced Apoptosis and Express Unique Pro-Apoptotic Gene Signature

Although extensive studies have demonstrated the functional impairment of antigen-specific CD4(+) and CD8(+) T-cells during chronic hepatitis C virus (HCV) infection, the functional status of global CD4(+) and CD8(+) T-cells remains unclear. In this report, we recruited 42 long-term (~20 years) trea...

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Detalles Bibliográficos
Autores principales: Zhao, Bin-Bin, Zheng, Su-Jun, Gong, Lu-Lu, Wang, Yu, Chen, Cai-Feng, Jin, Wen-Jing, Zhang, Ding, Yuan, Xiao-Hui, Guo, Jian, Duan, Zhong-Ping, He, You-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794995/
https://www.ncbi.nlm.nih.gov/pubmed/24130824
http://dx.doi.org/10.1371/journal.pone.0077008