Oxidative Stress Induced Mitochondrial Protein Kinase A Mediates Cytochrome C Oxidase Dysfunction

Previously we showed that Protein kinase A (PKA) activated in hypoxia and myocardial ischemia/reperfusion mediates phosphorylation of subunits I, IVi1 and Vb of cytochrome c oxidase. However, the mechanism of activation of the kinase under hypoxia remains unclear. It is also unclear if hypoxic stres...

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Detalles Bibliográficos
Autores principales: Srinivasan, Satish, Spear, Joseph, Chandran, Karunakaran, Joseph, Joy, Kalyanaraman, Balaraman, Avadhani, Narayan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795003/
https://www.ncbi.nlm.nih.gov/pubmed/24130844
http://dx.doi.org/10.1371/journal.pone.0077129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795003/
https://www.ncbi.nlm.nih.gov/pubmed/24130844
http://dx.doi.org/10.1371/journal.pone.0077129

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