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Oxidative Stress Induced Mitochondrial Protein Kinase A Mediates Cytochrome C Oxidase Dysfunction

Previously we showed that Protein kinase A (PKA) activated in hypoxia and myocardial ischemia/reperfusion mediates phosphorylation of subunits I, IVi1 and Vb of cytochrome c oxidase. However, the mechanism of activation of the kinase under hypoxia remains unclear. It is also unclear if hypoxic stres...

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Detalles Bibliográficos
Autores principales:	Srinivasan, Satish, Spear, Joseph, Chandran, Karunakaran, Joseph, Joy, Kalyanaraman, Balaraman, Avadhani, Narayan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795003/ https://www.ncbi.nlm.nih.gov/pubmed/24130844 http://dx.doi.org/10.1371/journal.pone.0077129

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