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A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus
Viruses within a family often vary in their cellular tropism and pathogenicity. In many cases, these variations are due to viruses switching their specificity from one cell surface receptor to another. The structural requirements that underlie such receptor switching are not well understood especial...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795024/ https://www.ncbi.nlm.nih.gov/pubmed/24130487 http://dx.doi.org/10.1371/journal.ppat.1003688 |