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A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus

Viruses within a family often vary in their cellular tropism and pathogenicity. In many cases, these variations are due to viruses switching their specificity from one cell surface receptor to another. The structural requirements that underlie such receptor switching are not well understood especial...

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Detalles Bibliográficos
Autores principales: Neu, Ursula, Allen, Stacy-ann A., Blaum, Bärbel S., Liu, Yan, Frank, Martin, Palma, Angelina S., Ströh, Luisa J., Feizi, Ten, Peters, Thomas, Atwood, Walter J., Stehle, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795024/
https://www.ncbi.nlm.nih.gov/pubmed/24130487
http://dx.doi.org/10.1371/journal.ppat.1003688