Caspase-1 Promotes Epstein-Barr Virus Replication by Targeting the Large Tegument Protein Deneddylase to the Nucleus of Productively Infected Cells

The large tegument proteins of herpesviruses contain N-terminal cysteine proteases with potent ubiquitin and NEDD8-specific deconjugase activities, but the function of the enzymes during virus replication remains largely unknown. Using as model BPLF1, the homologue encoded by Epstein-Barr virus (EBV...

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Detalles Bibliográficos
Autores principales: Gastaldello, Stefano, Chen, Xinsong, Callegari, Simone, Masucci, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795028/
https://www.ncbi.nlm.nih.gov/pubmed/24130483
http://dx.doi.org/10.1371/journal.ppat.1003664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795028/
https://www.ncbi.nlm.nih.gov/pubmed/24130483
http://dx.doi.org/10.1371/journal.ppat.1003664

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