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CXCR3-Dependent CD4(+) T Cells Are Required to Activate Inflammatory Monocytes for Defense against Intestinal Infection

Chemokines and their receptors play a critical role in orchestrating immunity to microbial pathogens, including the orally acquired Th1-inducing protozoan parasite Toxoplasma gondii. Chemokine receptor CXCR3 is associated with Th1 responses, and here we use bicistronic CXCR3-eGFP knock-in reporter m...

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Detalles Bibliográficos
Autores principales: Cohen, Sara B., Maurer, Kirk J., Egan, Charlotte E., Oghumu, Steve, Satoskar, Abhay R., Denkers, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795032/
https://www.ncbi.nlm.nih.gov/pubmed/24130498
http://dx.doi.org/10.1371/journal.ppat.1003706