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Restoration of CMV-Specific-CD4 T Cells with ART Occurs Early and Is Greater in Those with More Advanced Immunodeficiency

OBJECTIVES: Restoration of Cytomegalovirus-specific-CD4 T cell (CMV-Sp-CD4) responses partly accounts for the reduction of CMV-disease with antiretroviral-therapy (ART), but CMV-Sp-CD4 may also drive immune activation and immunosenescence. This study characterized the dynamics of CMV-Sp-CD4 after AR...

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Detalles Bibliográficos
Autores principales: Hsu, Denise C., Kerr, Stephen J., Iampornsin, Thatri, Pett, Sarah L., Avihingsanon, Anchalee, Thongpaeng, Parawee, Zaunders, John J., Ubolyam, Sasiwimol, Ananworanich, Jintanat, Kelleher, Anthony D., Cooper, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795037/
https://www.ncbi.nlm.nih.gov/pubmed/24130889
http://dx.doi.org/10.1371/journal.pone.0077479