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Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity
Botulinum neurotoxins (BoNTs) are produced by Clostridium botulinum and cause the fatal disease botulism, a flaccid paralysis of the muscle. BoNTs are released together with several auxiliary proteins as progenitor toxin complexes (PTCs) to become highly potent oral poisons. Here, we report the stru...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795040/ https://www.ncbi.nlm.nih.gov/pubmed/24130488 http://dx.doi.org/10.1371/journal.ppat.1003690 |