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Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity
Botulinum neurotoxins (BoNTs) are produced by Clostridium botulinum and cause the fatal disease botulism, a flaccid paralysis of the muscle. BoNTs are released together with several auxiliary proteins as progenitor toxin complexes (PTCs) to become highly potent oral poisons. Here, we report the stru...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795040/ https://www.ncbi.nlm.nih.gov/pubmed/24130488 http://dx.doi.org/10.1371/journal.ppat.1003690 |