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Targeting c-MYC with T-Cells

Over-expression of the proto-oncogene c-MYC is frequently observed in a variety of tumors and is a hallmark of Burkitt´s lymphoma. The fact that many tumors are oncogene-addicted to c-MYC, renders c-MYC a powerful target for anti-tumor therapy. Using a xenogenic vaccination strategy by immunizing C5...

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Detalles Bibliográficos
Autores principales: Helm, Florian, Kammertoens, Thomas, Lehmann, Frank M., Wilke, Andrea, Bruns, Heiko, Mautner, Josef, Bornkamm, Georg W., Gerbitz, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795085/
https://www.ncbi.nlm.nih.gov/pubmed/24130880
http://dx.doi.org/10.1371/journal.pone.0077375