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The Many Faces of Aire in Central Tolerance

Although the role that Autoimmune Regulator (Aire) plays in the induction of central tolerance is well known, the precise cellular and molecular mechanisms are still unclear and debated. In the prevailing view, Aire serves mainly as a direct inducer of tissue-specific antigens. However, there is a g...

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Detalles Bibliográficos
Autores principales: Laan, Martti, Peterson, Pärt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795325/
https://www.ncbi.nlm.nih.gov/pubmed/24130560
http://dx.doi.org/10.3389/fimmu.2013.00326