Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects

In asthmatic patients, inhalation of hyperosmolar saline or D-mannitol (D-M) elicits bronchoconstriction, but in healthy subjects exercise causes bronchodilation. Hyperventilation causes drying of airway surface liquid (ASL) and increases its osmolarity. Hyperosmolar challenge of airway epithelium r...

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Detalles Bibliográficos
Autores principales: Fedan, Jeffrey S., Thompson, Janet A., Ismailoglu, U. Burcin, Jing, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795350/
https://www.ncbi.nlm.nih.gov/pubmed/24130533
http://dx.doi.org/10.3389/fphys.2013.00287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795350/
https://www.ncbi.nlm.nih.gov/pubmed/24130533
http://dx.doi.org/10.3389/fphys.2013.00287

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