Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells

Cancer cells often develop drug resistance. In cisplatin-resistant HeLa cisR cells, fibroblast growth factor 13 (FGF13/FHF2) gene and protein expression was strongly upregulated, and intracellular platinum concentrations were kept low. When the FGF13 expression was suppressed, both the cells' r...

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Detalles Bibliográficos
Autores principales: Okada, Tomoko, Murata, Kazuhiro, Hirose, Ryoma, Matsuda, Chie, Komatsu, Tsunehiko, Ikekita, Masahiko, Nakawatari, Miyako, Nakayama, Fumiaki, Wakatsuki, Masaru, Ohno, Tatsuya, Kato, Shingo, Imai, Takashi, Imamura, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795355/
https://www.ncbi.nlm.nih.gov/pubmed/24113164
http://dx.doi.org/10.1038/srep02899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795355/
https://www.ncbi.nlm.nih.gov/pubmed/24113164
http://dx.doi.org/10.1038/srep02899

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