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Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor
A single human cell contains more than 5.0 × 10(5) copies of long interspersed element-1 (L1), 80–100 of which are competent for retrotransposition (L1-RTP). Recent observations have revealed the presence of de novo L1 insertions in various tumors, but little is known about its mechanism. Here, we f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795476/ https://www.ncbi.nlm.nih.gov/pubmed/23208499 http://dx.doi.org/10.1038/onc.2012.516 |