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Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor

A single human cell contains more than 5.0 × 10(5) copies of long interspersed element-1 (L1), 80–100 of which are competent for retrotransposition (L1-RTP). Recent observations have revealed the presence of de novo L1 insertions in various tumors, but little is known about its mechanism. Here, we f...

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Detalles Bibliográficos
Autores principales: Okudaira, N, Okamura, T, Tamura, M, Iijma, K, Goto, M, Matsunaga, A, Ochiai, M, Nakagama, H, Kano, S, Fujii-Kuriyama, Y, Ishizaka, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795476/
https://www.ncbi.nlm.nih.gov/pubmed/23208499
http://dx.doi.org/10.1038/onc.2012.516