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Structural and biochemical analysis of a thermostable membrane-bound stomatin-specific protease

Membrane-bound proteases are involved in various regulatory functions. The N-terminal region of PH1510p (1510-N) from the hyperthermophilic archaeon Pyrococcus horikoshii is a serine protease with a catalytic Ser–Lys dyad (Ser97 and Lys138), and specifically cleaves the C-terminal hydrophobic region...

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Detalles Bibliográficos
Autores principales: Yokoyama, Hideshi, Kobayashi, Daisuke, Takizawa, Naoto, Fujii, Satoshi, Matsui, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795559/
https://www.ncbi.nlm.nih.gov/pubmed/24121343
http://dx.doi.org/10.1107/S0909049513021328